Figure 3.

Acute changes in motor activity after Hcrt-1 administration. a: A representative actigraph record (5 min bins) showing the activity level of a dog during the 2 h period following Hcrt-1 (3 µg/kg) and normal saline administration. Hcrt-1 produced an increase in motor activity within 5 minutes of injection that persisted for 60 minutes. b: The increase of motor activity was statistically significant at 0-30 and 30-60 minutes after Hcrt-1 administration (n=6), as compared to saline control (n=6). In b values are mean ±SE, *p<0.05; **p<0.01, Newman-Keuls test.